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          科學(xué)家揭秘為何冬季多發(fā)流感
          Scientists discover why flu strikes in winter
          [ 2008-03-05 09:17 ]

          Experts believe they have now finally solved the tricky question of why winter is notoriously known as the flu season.

          It is a mystery that has baffled doctors for decades.

          But experts believe they have now finally solved the tricky question of why winter is notoriously known as the flu season.

          According to new research, the influenza virus coats itself in a protective fatty shield that is tough enough to withstand cold temperatures.

          The butter-like material only melts when it hits the respiratory tract, leaving the virus free to infect cells - a process scientists say is like an M&M melting in the mouth.

          However, in warmer outdoor temperatures, the protective coating melts before it reaches a person or an animal, killing the germs before they can infect someone.

          Joshua Zimmerberg, from the National Institute of Child Health and Human Development (NICHD), in the US, which led the study, said: 'Like an M&M in your mouth, the protective covering melts when it enters the respiratory tract.

          'It's only in this liquid phase that the virus is capable of entering a cell to infect it.'

          In the past scientists have worked on theories that flu is more common in winter because people spend more time inside or the radiation from the sun in summer kills off germs.

          But no research has successfully explained the spread of the disease.

          Researchers have already claimed that the report, which is published in the journal Nature Chemical Biology, could lead to new ways to prevent and treat flu.

          Duane Alexander, the director of NICHD, said: 'The study results open new avenues of research for thwarting winter flu outbreaks.

          'Now that we understand how the flu virus protects itself so that it can spread from person to person, we can work on ways to interfere with that protective mechanism.'

          Influenza and other respiratory viruses are spread in small droplets broadcast by coughing, sneezing and talking and which can also settle onto surfaces, to be picked up on fingertips.

           

          (Agencies)

          為何冬季為多發(fā)流感?

          這可是困擾了醫(yī)生們幾十年的一個(gè)謎。

          不過,專家們現(xiàn)在終于解開了這個(gè)難題。

          一項(xiàng)最新研究發(fā)現(xiàn),流感病毒表面包有一層脂肪保護(hù)外殼,這種外殼十分堅(jiān)硬,能抵御嚴(yán)寒。

          這種油狀物質(zhì)在進(jìn)入呼吸道后才會(huì)融化,病毒被釋放后即會(huì)感染細(xì)胞。科學(xué)家稱這一過程如同M&M巧克力豆在嘴里融化。

          然而,在溫度較高的環(huán)境下,這層保護(hù)殼在進(jìn)入人體或動(dòng)物體內(nèi)之前就會(huì)融化,因此病毒在感染細(xì)胞之前即被殺死。

          研究負(fù)責(zé)人、美國(guó)兒童健康與人類發(fā)展研究所的約瑟華?茲姆博格說:“這層保護(hù)殼在進(jìn)入呼吸道時(shí)即會(huì)融化,就像放入口中的M&M巧克力豆一樣。”

          “而就在這一液態(tài)階段,病毒才得以入侵并感染細(xì)胞。”

          科學(xué)家們過去一直在研究冬季易發(fā)流感的原因,一些理論稱這是因?yàn)槎救藗兌嘣谑覂?nèi)活動(dòng),或是因?yàn)橄募镜年?yáng)光輻射會(huì)殺死細(xì)菌。

          但沒有一項(xiàng)研究能真正解釋流感傳播的原因。

          研究人員們稱,這項(xiàng)研究成果能為防治流感提供新辦法。研究報(bào)告將在《自然化學(xué)生物學(xué)》期刊上發(fā)表。

          美國(guó)兒童健康與人類發(fā)展研究所主任杜安尼?亞歷山大說:“研究結(jié)果為控制冬季流感爆發(fā)開辟了新途徑。”

          “現(xiàn)在我們明白了流感病毒是如何保護(hù)自己并在人際間傳播的,因此我們可以研究如何‘干擾’這種保護(hù)機(jī)制。”

          流感及其他呼吸道病毒主要通過咳嗽、打噴嚏或說話時(shí)散播的飛沫傳播,它也會(huì)附著在物體表面,通過被污染的手指接觸傳染。

           

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