Should gene-editing be performed on human embryos?

Editor's note: He Jiankui, a biological researcher in Shenzhen, Guangdong province, announced on Monday that he has helped create the world's first genetically edited babies, Lulu and Nana, via in-vitro fertilization with gene-editing technology that immunized them from contracting HIV. The claim has stirred heated discussions on the internet. Forum readers share their opinions.

ceciliazhang (China)

I think I can understand gene-editing technique is used to prevent genetic disease, but shouldn't we figure out what will be the long-term effects on the two girls before the experiment is carried out? What will their potential offspring inherit? At the moment we just have no idea of what might come out of the gene-editing Pandora's Box.